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Jaakko Lappalainen Selected Research

Alcoholism (Alcohol Abuse)

3/2007Mutation screen of the GAD2 gene and association study of alcoholism in three populations.
9/2006Gamma-aminobutyric acid type A receptors and alcoholism: intoxication, dependence, vulnerability, and treatment.
3/2006Association between two mu-opioid receptor gene (OPRM1) haplotype blocks and drug or alcohol dependence.
11/2005ADH4 gene variation is associated with alcohol and drug dependence: results from family controlled and population-structured association studies.
4/2005Association between alcoholism and gamma-amino butyric acid alpha2 receptor subtype in a Russian population.
9/2002Association study of alcoholism subtypes with a functional promoter polymorphism in the serotonin transporter protein gene.
9/2002A functional neuropeptide Y Leu7Pro polymorphism associated with alcohol dependence in a large population sample from the United States.

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Jaakko Lappalainen Research Topics

Disease

7Alcoholism (Alcohol Abuse)
03/2007 - 09/2002
5Opioid-Induced Constipation
11/2016 - 09/2013
4Pain (Aches)
11/2016 - 09/2013
4Cocaine-Related Disorders (Cocaine Addiction)
03/2014 - 02/2004
3Subarachnoid Hemorrhage (Aneurysmal Subarachnoid Hemorrhage)
05/2009 - 10/2007
3Substance-Related Disorders (Drug Abuse)
06/2006 - 11/2005
2Traumatic Brain Injuries (Traumatic Brain Injury)
06/2016 - 01/2015
2Cerebral Infarction
05/2009 - 08/2008
2Depressive Disorder (Melancholia)
03/2008 - 01/2004
2Schizophrenia (Dementia Praecox)
06/2006 - 02/2004
1Diarrhea
11/2016
1Arthralgia (Joint Pain)
11/2016
1Constipation
10/2015
1Cancer Pain
10/2015
1Hemorrhage
05/2009
1Hematoma
05/2009
1Brain Ischemia (Cerebral Ischemia)
05/2009
1Infarction (Infarctions)
08/2008
1Brain Injuries (Brain Injury)
10/2007
1Paranoid Disorders (Paranoia)
06/2007
1Mental Disorders (Mental Disorder)
10/2006
1Substance Withdrawal Syndrome (Withdrawal Symptoms)
09/2006
1Post-Traumatic Stress Disorders (Post Traumatic Stress Disorder)
06/2006
1Alzheimer Disease (Alzheimer's Disease)
06/2006
1Mood Disorders (Mood Disorder)
06/2006
1Opioid-Related Disorders (Opiate Addiction)
11/2005

Drug/Important Bio-Agent (IBA)

6Opioid Analgesics (Opioids)IBA
11/2016 - 09/2013
4naloxegolIBA
11/2016 - 09/2013
3Brain-Derived Neurotrophic Factor (BDNF)IBA
08/2008 - 06/2006
3gamma-Aminobutyric Acid (GABA)IBA
03/2007 - 01/2004
2Blood Alcohol ContentIBA
06/2016 - 01/2015
2Narcotic Antagonists (Opioid Antagonists)IBA
06/2014 - 09/2013
2Mixed Function Oxygenases (Monooxygenases)IBA
03/2014 - 02/2013
2Dopamine (Intropin)FDA LinkGeneric
03/2014 - 02/2013
2Disulfiram (Antabuse)FDA Link
03/2014 - 02/2013
2EnzymesIBA
02/2013 - 03/2007
2Cocaine (Cocaine HCl)IBA
06/2007 - 11/2005
2Butyric Acid (Butanoic Acid)IBA
03/2007 - 04/2005
2Glutamic Acid (Glutamate)FDA Link
03/2007 - 01/2004
2NicotineFDA Link
10/2006 - 09/2006
1LaxativesIBA
10/2015
1Buprenorphine (Subutex)FDA LinkGeneric
03/2014
1PolymersIBA
09/2013
1Norepinephrine (Noradrenaline)FDA LinkGeneric
02/2013
1CopperIBA
02/2013
1CatecholaminesIBA
02/2013
1fibrin fragment D (D-dimer)IBA
05/2009
1Glucose (Dextrose)FDA LinkGeneric
05/2009
1ApolipoproteinsIBA
05/2009
1Apolipoproteins E (ApoE)IBA
05/2009
1Apolipoprotein E2IBA
05/2009
1valylvaline (Val-Val)IBA
08/2008
11-(2-(dodecyloxy)ethyl)pyrrolidine hydrochloride (DEP)IBA
03/2008
1Dopamine beta-HydroxylaseIBA
06/2007
1Ethanol (Ethyl Alcohol)IBA
03/2007
1GABA-A Receptors (GABA(A) Receptor)IBA
09/2006
1Pharmaceutical PreparationsIBA
03/2006
1mu Opioid Receptors (mu Opioid Receptor)IBA
03/2006
1calcyonIBA
02/2004
1Serotonin Plasma Membrane Transport Proteins (Serotonin Transporter)IBA
09/2002
1Proteins (Proteins, Gene)FDA Link
09/2002
1Neuropeptide YIBA
09/2002

Therapy/Procedure

2Drug Therapy (Chemotherapy)
02/2013 - 09/2006
1Self Administration (Administration, Self)
06/2007